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The department has 58 in-patients beds and 30 day-care beds with additional out-patients facilities (100 patients/day). Regarding myeloma, there are three full-time consultants dedicated to the care of https://play-bookofra.com/ myeloma patients. A large bone marrow transplantation unit performs more than 100 allogeneic transplants per year. There are three full time consultants dedicated to the management of these patients.

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The DRK-BSD has developed and manufactured numerous cell-based therapies and has successfully brought three ATMPs to national marketing authorization in Germany. The Paul-Ehrlich-Institut is the Federal Institute for Vaccines and Biomedicines in Germany, employs some 800 staff, and reports to the German Federal Ministry of Health. It is the German regulatory authority in the field of vaccines and biomedicinal products assessing https://www.ebay-kleinanzeigen.de/s-spielautomat/k0 and monitoring the benefit-risk balance before, during and after the marketing authorisation of these medicinal products. The combination of regulatory and research tasks at the PEI is unique among the European medicines agencies. Due to this sui generis position, the institute is especially qualified to provide science-based expert advice on questions concerning the quality, efficacy, and safety of vaccines and biomedicines.

It currently has 41 members based in 29 countries across Europe and further afield. It also had a number of associate members from the AL amyloidosis community. DRK-BSD’s role within the CARAMBA consortium consists in the development of manufacturing and quality control processes for the car modified cell product, regulatory affairs, as well as the technology transfer to collaborating centers. The DRK-Blutspendedienst (DRK-BSD) is part of the German Red Cross Blood Service Baden-Württemberg-Hessen gGmbH which consists of 18 sites and institutes across Germany. The DRK-BSD runs state of the art GMP facilities and has long-standing expertise in GMP manufacturing, quality control, quality management and pharmaceutical regulation. As such the DRK-BSD has decade-long experience in producing blood products, cell based medicines and advanced therapeutic medicinal products .

Further, NBE contributes significantly to the identification and protection of intellectual property from results of the CARAMBA project and commercial translation of the SLAMF7 CAR-T cell products. NBE is a Swiss SME that has been founded in 2012, currently employing 23 employees, that has developed a variety of technology platforms for the development of antibodies and next-generation antibody drug conjugates for improved cancer therapy. Dr. Ulf Grawunder, CEO of NBE-Therapeutics and successful Biotech entrepreneur has more than 15 years of commercial expertise in the field of developing antibody-based anti-cancer therapeutics. Using NBE’ s antibody discovery development and engineering capabilities, NBE can on one hand provide optimal binding domains and/or input for the optimal design of specific for the SLAMF7 target, as well as providing input in the design of the optimal CAR format. Also, NBE has developed proprietary technologies for the development of site-specifically conjugated ADCs coupled to ultra-potent anthracycline toxophores. MPE is an umbrella organisation of myeloma patient groups and associations. It is registered as a non-profit organisation under Belgian law and its headquarter is in Brussels.

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